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Fernando F Costa Selected Research

Interleukin-6 (Interleukin 6)

1/2023Molecular and cellular effects of in vivo chronic intravascular hemolysis and anti-inflammatory therapeutic approaches.
5/2020High levels of proinflammatory cytokines IL-6 and IL-8 are associated with a poor clinical outcome in sickle cell anemia.
1/2018Interleukin-6 G-174C polymorphism predicts higher risk of stroke in sickle cell anaemia.

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Fernando F Costa Research Topics

Disease

40Sickle Cell Anemia (Hemoglobin S Disease)
03/2023 - 02/2002
13Hemolysis
03/2023 - 05/2003
12Inflammation (Inflammations)
03/2023 - 09/2012
9Thalassemia
04/2021 - 09/2002
6beta-Thalassemia (Cooley's Anemia)
03/2024 - 01/2005
5Stroke (Strokes)
11/2023 - 07/2014
5Neoplasms (Cancer)
07/2023 - 04/2003
5Anemia
03/2023 - 05/2003
5Multiple Myeloma
03/2008 - 01/2003
3Hemoglobin SC Disease (Disease, Hemoglobin SC)
03/2024 - 04/2015
3Disease Progression
07/2022 - 11/2007
3Priapism
05/2020 - 09/2004
3Acute Chest Syndrome
05/2020 - 09/2004
2Reticulocytosis
01/2023 - 05/2003
2Macular Degeneration (Age-Related Maculopathy)
11/2021 - 01/2021
2alpha-Thalassemia
04/2021 - 02/2019
2Osteonecrosis (Kienbock's Disease)
05/2020 - 04/2015
2Pain (Aches)
02/2019 - 08/2008
2Iron Deficiencies
10/2017 - 01/2009
2Pulmonary Hypertension
06/2015 - 09/2012
2BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2014 - 07/2009
2Leukocytosis (Pleocytosis)
06/2012 - 04/2007
2Myocardial Infarction
10/2008 - 08/2004
2Adenocarcinoma
07/2007 - 04/2003
2Colorectal Neoplasms (Colorectal Cancer)
07/2007 - 04/2003
2Albuminuria
12/2006 - 04/2006
1Premature Birth (Birth, Premature)
03/2024
1Hematologic Neoplasms (Hematological Malignancy)
07/2023
1Pyruvate Kinase Deficiency of Red Cells
10/2022
1Cholelithiasis
04/2021
1Leg Ulcer
05/2020
1Venous Thromboembolism
02/2019
1Congenital Hemolytic Anemia (Hemolytic Anemia, Congenital)
05/2017

Drug/Important Bio-Agent (IBA)

12Proteins (Proteins, Gene)FDA Link
01/2023 - 06/2006
9Hemoglobins (Hemoglobin)IBA
03/2023 - 02/2008
9CytokinesIBA
05/2020 - 01/2005
8GlobinsIBA
03/2023 - 03/2002
7Hydroxyurea (Hydrea)FDA LinkGeneric
01/2023 - 09/2004
6IronIBA
03/2023 - 10/2006
6DNA (Deoxyribonucleic Acid)IBA
04/2021 - 02/2002
6beta-Globins (beta Globin)IBA
01/2018 - 01/2005
5Nitric Oxide (Nitrogen Monoxide)FDA Link
11/2023 - 04/2008
5Heme (Haem)IBA
03/2023 - 05/2017
5EnzymesIBA
01/2018 - 04/2003
4Fetal Hemoglobin (Hemoglobin F)IBA
04/2021 - 08/2008
3Sickle HemoglobinIBA
03/2023 - 01/2013
3Interleukin-6 (Interleukin 6)IBA
01/2023 - 01/2018
3BilirubinIBA
04/2021 - 05/2003
3Messenger RNA (mRNA)IBA
01/2016 - 09/2006
3EndostatinsIBA
06/2015 - 01/2003
3Codon (Codons)IBA
01/2009 - 02/2006
3Folic Acid (Vitamin M)FDA LinkGeneric
03/2008 - 10/2006
2Interleukin-10 (Interleukin 10)IBA
01/2023 - 08/2011
2Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
01/2023 - 04/2011
2NADPH Oxidases (NAD(P)H oxidase)IBA
11/2016 - 01/2008
2AntigensIBA
01/2016 - 02/2002
2Guanosine Monophosphate (5' Guanylic Acid)IBA
01/2016 - 09/2008
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
04/2015 - 04/2011
2Nitric Oxide Synthase (NO Synthase)IBA
01/2015 - 04/2011
2Dasatinib (BMS 354825)FDA Link
10/2014 - 01/2014
2Imatinib Mesylate (Gleevec)FDA Link
10/2014 - 01/2014
2glucose-6-phosphate dehydrogenase A-IBA
07/2014 - 05/2003
2Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
07/2011 - 09/2008
2Methylenetetrahydrofolate Reductase (NADPH2) (Methylenetetrahydrofolate Reductase)IBA
03/2008 - 07/2007
2alpha-GlobinsIBA
02/2008 - 01/2007
2Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA
10/2007 - 10/2007
2Granulocyte Colony-Stimulating Factor (G-CSF)IBA
04/2007 - 04/2006
2CreatinineIBA
12/2006 - 04/2006
2Platelet Membrane GlycoproteinsIBA
10/2004 - 08/2004
2Glutathione Transferase (Glutathione S-Transferase)IBA
04/2003 - 01/2003
1ethylenebis(isothiocyanate) (EBIS)IBA
03/2023
1phenylhydrazine (phenylhydrazine hydrochloride)IBA
01/2023
1Endothelin-1 (Endothelin 1)IBA
01/2023
1Glutamine (L-Glutamine)FDA Link
01/2023
1InterleukinsIBA
01/2023
1mitapivatIBA
10/2022
1Biomarkers (Surrogate Marker)IBA
07/2022
1Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
01/2022
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2022
1Complement System Proteins (Complement)IBA
11/2021
1Apolipoproteins E (ApoE)IBA
01/2021
1DNA-Directed DNA Polymerase (Polymerases, DNA)IBA
01/2021
1Interleukin-8 (Interleukin 8)IBA
05/2020
13,4-dihydroxybenzohydroxamic acidIBA
01/2020
1Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
01/2020
1Serotonin (5 Hydroxytryptamine)IBA
01/2020
1ErythropoietinFDA Link
02/2019
1HemopexinIBA
01/2019
1AntioxidantsIBA
01/2018
1Peroxidase (Myeloperoxidase)IBA
01/2018
1Reducing AgentsIBA
01/2018
1PolymersIBA
01/2018
1hemoglobin A2'IBA
10/2017
1hemoglobin BristolIBA
05/2017

Therapy/Procedure

11Therapeutics
07/2023 - 09/2004
1Cesarean Section (Caesarean Section)
03/2024
1Blood Transfusion (Blood Transfusions)
03/2024
1Prenatal Care (Care, Prenatal)
03/2024
1Palliative Care (Palliative Therapy)
07/2023
1Ligation
10/2017